Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331372 | 0.83 | CSNK2A1 (0.68) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3333529 | 0.76 | KMT2A (0.81) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL11940597 | 0.74 | CSNK2A1 (0.79) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3332413 | 0.74 | KMT2A (0.72) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3334350 | 0.73 | CSNK2A1 (0.74) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3333973 | 0.73 | CSNK2A1 (0.84) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3333434 | 0.72 | CSNK2A1 (0.60) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL3334830 | 0.71 | CSNK2A1 (0.77) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL11939631 | 0.71 | PIK3CD (0.82) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 | |
| SCHEMBL14149635 | 0.70 | CSNK2A1 (0.68) | CSNK2A1KDM4EHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471529-A2 | Kinase Inhibitors for Preventing or Treating Pathogen Infection and Method of Use Thereof | Emory University (US) | 2012-07-04 | — | — | EP | disclosed |