SCHEMBL1194014

SCHEMBL1194014

Cc1cc(C(N)=O)ccc1C(=O)N1CCCCC1.NC(=O)c1ccc(C(=O)N2CCCCCCCCCC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 10/20 0.57
ALDH1A1 P00352 2/20 0.57
KMT2A Q03164 1/20 0.56
TSHR P16473 1/20 0.54
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
CNR2 P34972 1/20 0.48
POLB P06746 1/20 0.48
ATM Q13315 1/20 0.48
PLA2G7 Q13093 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1159852 1.00 HPGD (0.57) HPGDALDH1A1KMT2ATSHRCA12
SCHEMBL539053 1.00 HPGD (0.57) HPGDALDH1A1KMT2ATSHRCA12
Terephthalamide SCHEMBL1181439 0.97 HPGD (0.52) HPGDALDH1A1KMT2ATSHRCA12
SCHEMBL11454853 0.96 HPGD (0.54) HPGDALDH1A1KMT2ATSHRCA12
SCHEMBL542082 0.96 HPGD (0.54) HPGDALDH1A1KMT2ATSHRCA12
SCHEMBL5070484 0.94 HPGD (0.54) HPGDALDH1A1KMT2ATSHRCNR2
SCHEMBL13519382 0.88 KMT2A (0.45) HPGDALDH1A1KMT2ATSHR
SCHEMBL7772522 0.85 KMT2A (0.50) HPGDALDH1A1KMT2ATSHRCNR2
SCHEMBL6471454 0.85 HPGD (0.60) HPGDALDH1A1KMT2ATSHRCNR2
SCHEMBL11857269 0.84 HPGD (0.80) HPGDALDH1A1KMT2ATSHRCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861660-B1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH AMINO ACID HEAT STABILIZER DU PONT (US) 2018-09-05 EP disclosed
EP-2531704-B1 MUFFLER WITH INTEGRATED CATALYTIC CONVERTER AND POLYMERIC MUFFLER BODY DU PONT (US) 2018-05-23 EP disclosed
EP-2841504-B1 THERMOPLASTIC POLYAMIDE COMPOSITION DU PONT (US) 2016-11-30 EP disclosed
US-9080034-B2 Thermoplastic melt-mixed composition with amino acid heat stabilizer E I DU PONT DE NEMOURS AND COMPANY (US) 2015-07-14 US disclosed
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP disclosed
US-8952107-B2 Thermoplastic melt-mixed composition with polyetherol heat stabilizer E I DU PONT DE NEMOURS AND COMPANY (US) 2015-02-10 US disclosed
US-8906479-B2 Compositions of polyamide and ionomer E I DU PONT DE NEMOURS AND COMPANY (US) 2014-12-09 US disclosed
US-8871874-B2 Thermoplastic melt-mixed composition with epoxy-amino acid compound heat stabilizer and processes for their preparation E I DU PONT DE NEMOURS AND COMPANY (US) 2014-10-28 US disclosed
US-20130338263-A1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH POLYETHEROL HEAT STABILIZER E. I. DU PONT DE NEMOURS AND COMPANY 2013-12-19 US disclosed
US-20130338301-A1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH EPOXY-CARBOXYLIC ACID COMPOUND HEAT STABILIZER AND PROCESSES FOR THEIR PREPARATION E. I. DU PONT DE NEMOURS AND COMPANY 2013-12-19 US disclosed
EP-2307503-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. du Pont de Nemours and Company (US) 2011-04-13 EP disclosed
US-20110028621-A1 HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-03 US disclosed
WO-2010014801-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
WO-2010014795-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed
US-20100028580-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029821-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029819-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100029815-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
US-20100028581-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US disclosed
WO-2010014790-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO disclosed