Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 13/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702666 | 0.85 | CYP1A1 (0.74) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL30338912 | 0.78 | CYP1A1 (0.63) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL15296276 | 0.77 | CYP11B1 (0.64) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL21960161 | 0.76 | CYP11B1 (0.73) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL12302844 | 0.74 | CYP11B1 (0.65) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL744752 | 0.73 | CYP1A1 (0.61) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL4581721 | 0.73 | CYP11B1 (0.58) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL22869164 | 0.72 | CYP1A1 (0.55) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL32663058 | 0.72 | CYP1A1 (0.55) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 | |
| SCHEMBL21044298 | 0.72 | MKNK1 (0.64) | CYP1A1CYP1B1CYP11B2CYP11B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220091-B1 | REVERSE TRANSCRIPTASE INHIBITORS | ARDEA BIOSCIENCES INC (US) | 2012-07-25 | — | — | EP | disclosed |