Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948856 | 0.87 | PRCP (0.51) | PRCPGAAMAOAMAPTMEN1 | |
| SCHEMBL11948841 | 0.78 | PRCP (0.47) | PRCPGAAMAOAMAPTMEN1 | |
| SCHEMBL6986104 | 0.78 | PRCP (0.52) | PRCPGAAMAOAMAPTMEN1 | |
| SCHEMBL4120535 | 0.75 | PRCP (0.50) | PRCPGAAMAPTMEN1KMT2A | |
| SCHEMBL11948857 | 0.74 | PRCP (0.55) | PRCPGAAMAOAALDH1A1HSD17B10 | |
| SCHEMBL6229660 | 0.73 | PRCP (0.65) | PRCPGAAMAPTMEN1KMT2A | |
| SCHEMBL6229072 | 0.73 | PRCP (0.65) | PRCPGAAMAPTMEN1KMT2A | |
| SCHEMBL28801361 | 0.73 | PRCP (0.62) | PRCPGAAMAPTMEN1KMT2A | |
| SCHEMBL11948862 | 0.72 | PRCP (0.47) | PRCPGAAMAOAMAPTRECQL | |
| SCHEMBL11948844 | 0.72 | PRCP (0.46) | PRCPGAAMAOAGID4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232399-B2 | Chiral ligands, their preparation and uses thereof in asymmetric reactions | Li, Chao-Jun (CA) | 2012-07-31 | — | — | US | disclosed |