Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11949086 | 0.95 | S1PR1 (0.54) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15310448 | 0.95 | S1PR1 (0.54) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL11888795 | 0.87 | S1PR1 (0.53) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL11888796 | 0.87 | S1PR1 (0.53) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL11949091 | 0.83 | S1PR1 (0.59) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL4423227 | 0.82 | S1PR1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL4423223 | 0.82 | S1PR1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL11888781 | 0.82 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL15310353 | 0.82 | S1PR1 (0.58) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL11888769 | 0.82 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232319-B2 | Amino phosphate derivative and S1P receptor modulator having same as an active ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2012-07-31 | — | — | US | disclosed |