Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 14/20 | 0.85 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.85 |
| ▸ | ITGAL | P20701 | 14/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21194988 | 0.89 | ITGB2 (0.84) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL18837960 | 0.89 | ITGB2 (0.84) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL16834384 | 0.88 | ITGB2 (0.74) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL30081478 | 0.88 | ITGB2 (0.74) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL15780958 | 0.86 | ITGB2 (0.79) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL1358036 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL1358031 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL11868630 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL11869919 | 0.86 | ITGB2 (0.80) | ITGB2ICAM1ITGALALDH1A1POLB | |
| SCHEMBL15145360 | 0.86 | ITGB2 (0.74) | ITGB2ICAM1ITGALALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409880-B2 | Modulators of TLR3/dsRNA complex and uses thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-08-09 | — | — | US | disclosed |
| WO-2012099785-A2 | MODULATORS OF TLR3/DSRNA COMPLEX AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-07-26 | — | — | WO | disclosed |