Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR3 | O15455 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | BCKDK | O14874 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11498990 | 1.00 | TLR3 (0.80) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL11498991 | 1.00 | TLR3 (0.80) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL11498254 | 0.89 | TLR3 (0.77) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL11951242 | 0.89 | TLR3 (1.00) | TLR3NPSR1HPGDRXFP1BCKDK | |
| SCHEMBL11951244 | 0.89 | TLR3 (1.00) | TLR3NPSR1HPGDRXFP1BCKDK | |
| SCHEMBL11301956 | 0.89 | TLR3 (1.00) | TLR3NPSR1HPGDRXFP1BCKDK | |
| SCHEMBL11498253 | 0.89 | TLR3 (0.77) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL11951240 | 0.89 | TLR3 (0.77) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL17988516 | 0.89 | TLR3 (0.77) | TLR3NPSR1HPGDMEN1KMT2A | |
| SCHEMBL17988518 | 0.89 | TLR3 (0.77) | TLR3NPSR1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030019-A1 | TARGETING TLR3 FOR TREATMENT OF HEMATOPOIETIC STEM CELL PROLIFERATION-ASSOCIATED DISEASES OR DISORDERS | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-02-06 | — | — | WO | disclosed |
| US-9409880-B2 | Modulators of TLR3/dsRNA complex and uses thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-08-09 | — | — | US | disclosed |
| US-9409880-B2 | Modulators of TLR3/dsRNA complex and uses thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-08-09 | — | — | US | disclosed |
| US-9409880-B2 | Modulators of TLR3/dsRNA complex and uses thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2016-08-09 | — | — | US | disclosed |
| WO-2012099785-A2 | MODULATORS OF TLR3/DSRNA COMPLEX AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-07-26 | — | — | WO | disclosed |