Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1195191 | 1.00 | PTGS1 (0.56) | PTGS1NR1H3PTPN1NR1H2 | |
| SCHEMBL267405 | 1.00 | PTGS1 (0.56) | PTGS1NR1H3PTPN1NR1H2 | |
| SCHEMBL12522092 | 0.89 | PTGS1 (0.43) | PTGS1NR1H3PTPN1 | |
| SCHEMBL267408 | 0.88 | PTGS1 (0.51) | PTGS1NR1H3PTPN1 | |
| SCHEMBL262480 | 0.88 | PTGS1 (0.58) | PTGS1NR1H3PTPN1NR1H2 | |
| SCHEMBL267398 | 0.88 | PTGS1 (0.58) | PTGS1NR1H3PTPN1NR1H2 | |
| SCHEMBL267588 | 0.88 | PTGS1 (0.50) | PTGS1NR1H3PTPN1 | |
| SCHEMBL267085 | 0.87 | PTGS1 (0.59) | PTGS1NR1H3PTPN1 | |
| SCHEMBL12450194 | 0.87 | PTGS1 (0.59) | PTGS1NR1H3PTPN1 | |
| SCHEMBL267238 | 0.81 | PTGS1 (0.67) | PTGS1NR1H3PTPN1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893299-B2 | Acanthoic amide derivatives; inflammation, cancer, cachexia, cardiovascular disease, infections, diabetes, otitis media, sinusitis, transplant rejection | NEREUS PHARMACEUTICALS, INC. (US) | 2011-02-22 | — | — | US | disclosed |