Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 20/20 | 0.80 |
| ▸ | DYRK1B | Q9Y463 | 17/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447132 | 0.94 | DYRK1A (0.90) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10323428 | 0.93 | DYRK1A (0.89) | DYRK1ADYRK1B | |
| SCHEMBL10447103 | 0.89 | DYRK1A (1.00) | DYRK1ADYRK1B | |
| SCHEMBL10447105 | 0.89 | DYRK1A (0.90) | DYRK1ADYRK1B | |
| SCHEMBL10446748 | 0.89 | DYRK1A (0.87) | DYRK1ADYRK1B | |
| SCHEMBL11952861 | 0.89 | DYRK1A (0.63) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10323217 | 0.88 | DYRK1A (0.99) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10322587 | 0.88 | DYRK1A (0.86) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10322519 | 0.88 | DYRK1A (0.89) | DYRK1ADYRK1B | |
| SCHEMBL10323055 | 0.86 | DYRK1A (0.77) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098065-A1 | PYRIDO PYRIMIDINES FOR USE AS DYRK1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-07-26 | — | — | WO | disclosed |