Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methyl 2-Methylbutanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl 2-Methylbutanoate SCHEMBL8954886 | 0.89 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL108113 | 0.89 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL283261 | 0.89 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL1869834 | 0.89 | CA1 (0.46) | CA1CA2HSD17B10TSHRSMN1; SMN2 | |
| Methyl 2-Methylbutanoate SCHEMBL23358383 | 0.86 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL27352651 | 0.86 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL27502998 | 0.86 | CA1 (0.45) | CA1CA2HSD17B10TSHRSMN1; SMN2 | |
| Methyl 2-Methylbutanoate SCHEMBL28123513 | 0.86 | — | — | |
| Methyl 2-Methylbutanoate SCHEMBL27518909 | 0.84 | CA1 (0.43) | CA1CA2HSD17B10TSHRSMN1; SMN2 | |
| Methyl 2-Methylbutanoate SCHEMBL28264726 | 0.84 | CA1 (0.43) | CA1CA2HSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106610567-B | Method for producing a layer structure and method for forming a pattern | 三星SDI株式会社 | 2020-08-04 | — | — | CN | disclosed |
| US-7879961-B2 | Resin composition for organic insulating layer, method of manufacturing resin composition, and display panel including resin composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-02-01 | — | — | US | disclosed |
| US-7691915-B2 | Photosensitive resin composition for forming organic insulating film and device using the same | CHEIL INDUSTRIES INC. (KR) | 2010-04-06 | — | — | US | disclosed |
| US-7425479-B2 | Method of manufacturing a thin film transistor array panel | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-09-16 | — | — | US | disclosed |
| US-20080145786-A1 | Photosensitive Resin Composition for Forming Organic Insulating Film and Device Using the Same | CHEIL INDUSTRIES INC. (KR) | 2008-06-19 | — | — | US | disclosed |
| US-20080044961-A1 | THIN FILM TRANSISTOR ARRAY PANEL | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-02-21 | — | — | US | disclosed |
| US-20070184293-A1 | RESIN COMPOSITION FOR ORGANIC INSULATING LAYER, METHOD OF MANUFACTURING RESIN COMPOSITION, AND DISPLAY PANEL INCLUDING RESIN COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-08-09 | — | — | US | disclosed |
| US-20050127366-A1 | Thin film transistor array panel | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-06-16 | — | — | US | disclosed |