Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18386646 | 0.85 | CNR1 (0.41) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10163681 | 0.82 | HTT (0.47) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL13266198 | 0.79 | HTT (0.44) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10163908 | 0.79 | HTT (0.44) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10227071 | 0.79 | HTT (0.44) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16638686 | 0.79 | SMN1; SMN2 (0.67) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12642923 | 0.79 | SMN1; SMN2 (0.67) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL13465024 | 0.79 | GAA (0.55) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL14036502 | 0.79 | GAA (0.50) | GAAHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10979017 | 0.79 | GAA (0.59) | GAAHTTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995265-B1 | POLYARYLENE AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-08-01 | — | — | EP | disclosed |