SCHEMBL119637

SCHEMBL119637

O=C(NC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.59
TP53 P04637 3/20 0.59
KMT2A Q03164 2/20 0.56
CASP3 P42574 2/20 0.54
TLR2 O60603 2/20 0.53
MDM2 Q00987 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31276348 1.00 MDM4 (0.59) MDM4TP53KMT2ACASP3TLR2
SCHEMBL29455664 1.00 MDM4 (0.59) MDM4TP53KMT2ACASP3TLR2
SCHEMBL119688 1.00 MDM4 (0.59) MDM4TP53KMT2ACASP3TLR2
SCHEMBL5967446 1.00 MDM4 (0.59) MDM4TP53KMT2ACASP3TLR2
SCHEMBL29528770 1.00 MDM4 (0.59) MDM4TP53KMT2ACASP3TLR2
SCHEMBL15806918 0.94 MDM4 (0.56) MDM4TP53KMT2ACASP3TLR2
SCHEMBL25168212 0.93 MDM4 (0.53) MDM4TP53KMT2ACASP3TLR2
SCHEMBL6290889 0.93 MDM4 (0.53) MDM4TP53KMT2ACASP3TLR2
SCHEMBL22552830 0.93 MDM4 (0.53) MDM4TP53KMT2ACASP3TLR2
SCHEMBL31220290 0.93 MDM4 (0.53) MDM4TP53KMT2ACASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed