Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11967815 | 0.91 | DRD3 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL11967820 | 0.89 | MEN1 (0.42) | LMNA | |
| SCHEMBL6778387 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6777154 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL17485769 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL19196740 | 0.82 | DRD3 (0.48) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4739726 | 0.81 | — | — | |
| SCHEMBL6783375 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6780571 | 0.81 | — | — | |
| SCHEMBL6779071 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-B1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2012-08-22 | — | — | EP | claimed |