SCHEMBL11981035

SCHEMBL11981035

CC(C)(C)c1ccc(-n2c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PPARG P37231 5/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PPARA Q07869 2/20 0.43
PTGES O14684 1/20 0.40
KMT2A Q03164 1/20 0.39
PTGER4 P35408 1/20 0.39
TSPO P30536 1/20 0.39
HDAC4 P56524 1/20 0.39
NR1H4 Q96RI1 1/20 0.38
PMM2 O15305 1/20 0.38
MPI P34949 1/20 0.38
PHOSPHO1 Q8TCT1 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745994 1.00 KDM4E (0.55) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL24793159 0.98 KDM4E (0.53) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL24792718 0.98 KDM4E (0.53) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15445987 0.97 KDM4E (0.51) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15783211 0.97 KDM4E (0.55) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL16171587 0.97 KDM4E (0.48) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL20152270 0.97 KDM4E (0.48) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL17228096 0.97 KDM4E (0.48) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL15745993 0.96 KDM4E (0.50) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL24793869 0.95 KDM4E (0.49) KDM4EATML3MBTL1PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2492986-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2016-06-15 EP disclosed
US-9306174-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-05 US disclosed
US-9306174-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-05 US disclosed
US-9306175-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-05 US disclosed
US-9306175-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-05 US disclosed
EP-2595208-A1 LIGHT EMITTING ELEMENT Toray Industries, Inc. (JP) 2013-05-22 EP disclosed
US-20130105787-A1 LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2013-05-02 US disclosed
US-20130105787-A1 LIGHT EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2013-05-02 US disclosed
US-20120273767-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-11-01 US disclosed
US-20120205642-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD (JP) 2012-08-16 US disclosed