SCHEMBL119822

SCHEMBL119822

O=C(O)CN1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
KMT2A Q03164 3/20 0.46
FABP7 O15540 2/20 0.45
FABP5 Q01469 2/20 0.45
POLB P06746 2/20 0.44
ALDH1A1 P00352 4/20 0.44
CACNA1G O43497 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
LMNA P02545 2/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30481198 1.00 KDM4E (0.46) KDM4EKMT2AFABP7FABP5POLB
SCHEMBL31505489 1.00 KDM4E (0.46) KDM4EKMT2AFABP7FABP5POLB
SCHEMBL31398326 1.00 KDM4E (0.46) KDM4EKMT2AFABP7FABP5POLB
Water SCHEMBL4955373 0.99 KDM4E (0.45) KDM4EKMT2AFABP7FABP5POLB
SCHEMBL28078038 0.96 KDM4E (0.44) KDM4EKMT2AFABP7FABP5POLB
SCHEMBL3206093 0.95 KDM4E (0.43) KDM4EKMT2AFABP7FABP5POLB
SCHEMBL31542622 0.89 CYP1A2 (0.45) KDM4EKMT2APOLBALDH1A1CYP1A2
SCHEMBL13327274 0.89 POLB (0.52) KMT2AFABP7FABP5POLBALDH1A1
SCHEMBL22397770 0.89 POLB (0.52) KMT2AFABP7FABP5POLBALDH1A1
SCHEMBL3219970 0.86 FABP5 (0.49) KMT2AFABP7FABP5POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
US-12606817-B2 Methods of creating and screening DNA-encoded libraries X-CHEM, INC. (US) 2026-04-21 US disclosed
US-20230218765-A1 SMALL MOLECULE DEGRADERS OF SHP2 PROTEIN UNIV MICHIGAN REGENTS (US) 2023-07-13 US disclosed
WO-2023108031-A1 PRODRUGS FOR COMPOUNDS SPECIFIC TO GRANZYME B AND USES THEREOF CYTOSITE BIOPHARMA INC. (US) 2023-06-15 WO disclosed
EP-3515880-B1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF ENCODED LIBRARIES HITGEN INC (CN) 2023-05-10 EP disclosed
US-20200385709-A1 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES X-CHEM, INC. 2020-12-10 US disclosed
EP-3211126-B1 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES X CHEM INC (US) 2020-10-21 EP disclosed
EP-3653763-A1 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES X-Chem, Inc. (US) 2020-05-20 EP disclosed
EP-3211126-A1 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES X-Chem, Inc. (US) 2017-08-30 EP disclosed
WO-2002036808-A2 COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2002-05-10 WO disclosed
US-20020048763-A1 Human genome-derived single exon nucleic acid probes useful for gene expression analysis AMERSHAM PLC (GB) 2002-04-25 US disclosed
US-20020048800-A1 Myosin-like gene expressed in human heart and muscle GE HEALTHCARE LIMITED (GB) 2002-04-25 US disclosed
WO-2002026818-A2 HUMAN NEDD-1 AEOMICA, INT. (US) 2002-04-04 WO disclosed
WO-2002024718-A1 COMPOSITIONS AND METHODS RELATING TO PROSTATE SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2002-03-28 WO disclosed
WO-2002024750-A2 HUMAN KIDNEY TUMOR OVEREXPRESSED MEMBRANE PROTEIN 1 AEOMICA, INC. (US) 2002-03-28 WO disclosed
EP-1189612-A1 VLA-4 INHIBITOR COMPOUNDS Daiichi Pharmaceutical Co., Ltd. (JP) 2002-03-27 EP disclosed
WO-2001092524-A2 MYOSIN-LIKE GENE EXPRESSED IN HUMAN HEART AND MUSCLE AEOMICA, INC. (US) 2001-12-06 WO disclosed
WO-2001000206-A1 VLA-4 INHIBITOR COMPOUNDS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200385709-A1 METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES PCNA, DNA2, POLM KDM4E 3069/4885KMT2A 2085/4885FABP7 2512/4885
US-12606817-B2 Methods of creating and screening DNA-encoded libraries PCNA, DNA2, POLM KDM4E 4406/4885KMT2A 3602/4885FABP7 1854/4885
US-20230218765-A1 SMALL MOLECULE DEGRADERS OF SHP2 PROTEIN PTPN1, PTPRS, PPM1D KDM4E 251/4885KMT2A 675/4885FABP7 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.