Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL | Q9Y232 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | IAPP | P10997 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340131 | 0.81 | TDP1 (0.58) | CDYLKDM4EIAPPMTNR1ATDP1 | |
| Hydrochloric Acid SCHEMBL25414849 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Water SCHEMBL11575200 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Water SCHEMBL11572310 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Hydrochloric Acid SCHEMBL25415558 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Hydrochloric Acid SCHEMBL25412958 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Water SCHEMBL11574476 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Hydrochloric Acid SCHEMBL25414605 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Water SCHEMBL11571513 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D | |
| Water SCHEMBL11572069 | 0.80 | CDYL (0.54) | CDYLKDM4EBCHEACHEHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841321-B2 | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-23 | — | — | US | disclosed |
| US-8841321-B2 | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-23 | — | — | US | disclosed |
| EP-1898914-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-15 | — | — | EP | disclosed |
| US-20100048585-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-02-25 | — | — | US | disclosed |
| US-20100048585-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-02-25 | — | — | US | disclosed |
| WO-2007000435-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048585-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | NQO2, HRH1, HRH2 | CDYL 4360/4885KDM4E 3590/4885BCHE 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.