SCHEMBL11986124

SCHEMBL11986124

C=C(C)C(=O)OCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 8/20 0.52
MMP3 P08254 6/20 0.52
ALDH1A1 P00352 2/20 0.49
MAPT P10636 2/20 0.49
MMP1 P03956 1/20 0.48
MMP9 P14780 1/20 0.48
MMP13 P45452 1/20 0.48
KDM4E B2RXH2 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
POLB P06746 2/20 0.44
HPGD P15428 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HRH2 P25021 1/20 0.44
HRH1 P35367 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
PTGER4 P35408 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13289583 0.90 MAPT (0.47) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL16425295 0.90 MAPT (0.47) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL16541362 0.89 POLB (0.51) MMP2MMP3MAPTHDAC1HDAC2
SCHEMBL12172629 0.89 POLB (0.51) MMP2MMP3MAPTHDAC1HDAC2
SCHEMBL16657460 0.89 MAPT (0.46) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL7578689 0.87 MAPT (0.58) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL16425297 0.86 HDAC2 (0.45) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL16425296 0.86 MAPT (0.43) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL14275377 0.86 POLB (0.61) MMP2MMP3ALDH1A1MAPTMMP1
SCHEMBL29316150 0.86 POLB (0.58) MMP2MMP3ALDH1A1MAPTMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119016-A1 LIQUID CRYSTAL ALIGNMENT AGENT FOR PHOTO-ALIGNMENT, ALIGNING MEMBER, AND RETARDATION MEMBER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-03 US disclosed
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-20160289481-A1 COMPOSITION SET, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-10-06 US disclosed
US-20160289481-A1 COMPOSITION SET, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-10-06 US disclosed
US-20160280948-A1 COMPOSITION, SHAPED ARTICLE PRODUCTION METHOD, AND SHAPED ARTICLE SEIKO EPSON CORPORATION (JP) 2016-09-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-9080100-B2 Polymerizable liquid crystal composition JNC CORPORATION (JP) 2015-07-14 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-7931825-B2 Polymerizable composition ADEKA CORPORATION (JP) 2011-04-26 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100090163-A1 POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2010-04-15 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed
US-7488519-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-02-10 US disclosed
US-7476423-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-01-13 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed