SCHEMBL11986155

SCHEMBL11986155

C=C(C)C(=O)OCOc1ccc(C=CC(=O)Oc2ccc(S(=O)(=O)c3ccc(OC(=O)C=Cc4ccc(OCOC(=O)C(=C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
POLB P06746 3/20 0.43
PKM P14618 1/20 0.43
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ELANE P08246 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
NAMPT P43490 1/20 0.37
LMNA P02545 3/20 0.36
KDM4E B2RXH2 1/20 0.36
TTR P02766 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986164 0.85 KMT2A (0.43) MAPTPOLBPKMGAANPSR1
SCHEMBL16425364 0.84 SNCA (0.42) MAPTPOLBKMT2AMEN1ALDH1A1
SCHEMBL11986101 0.84 POLB (0.39) MAPTPOLBPKMGAANPSR1
SCHEMBL16425271 0.83 CA12 (0.50) MAPTPOLBGAAKMT2ATDP1
SCHEMBL11986162 0.83 CA12 (0.40) MAPTPOLBPKMGAANPSR1
SCHEMBL13481047 0.82 CA12 (0.43) MAPTPOLBKMT2AMEN1ALDH1A1
SCHEMBL13481041 0.82 CA12 (0.43) MAPTPOLBKMT2AMEN1ALDH1A1
SCHEMBL13963268 0.81 KMT2A (0.39) MAPTPOLBGAAKMT2AMEN1
SCHEMBL11986149 0.81 CYP1A1 (0.42) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL16425297 0.81 HDAC2 (0.45) MAPTKMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315728-B2 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film JNC CORPORATION (JP) 2016-04-19 US disclosed
US-8419973-B2 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8246855-B2 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC CORPORATION (JP) 2012-08-21 US disclosed
US-20100151154-A1 Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film CHISSO CORPORATION 2010-06-17 US disclosed
US-20100143612-A1 Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film CHISSO CORPORATION 2010-06-10 US disclosed
US-20100051866-A1 Polymerizable liquid crystal composition and optically anisotropic film using the same JNC PETROCHEMICAL CORPORATION (JP) 2010-03-04 US disclosed