Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | ACACA | Q13085 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734013 | 0.86 | ACACB (0.55) | ACACBACACA | |
| SCHEMBL12460526 | 0.84 | ACACB (0.43) | ACACBACACACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15489246 | 0.84 | ACACB (0.40) | ACACBACACACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2759750 | 0.84 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL16477702 | 0.83 | ACACB (0.33) | ACACBACACACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13527320 | 0.82 | ACACB (0.38) | ACACBACACACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL733886 | 0.82 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL2759754 | 0.82 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL737930 | 0.82 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL14129279 | 0.82 | ACACB (0.40) | ACACBACACACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962599-B1 | INSECTICIDE COMPOUNDS WITH IMPROVED EFFECT | BAYER IP GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-9204640-B2 | 2-acyloxy-pyrrolin-4-ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9204640-B2 | 2-acyloxy-pyrrolin-4-ones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| EP-2681191-B1 | 2-ACYLOXY-PYRROLIN-4-ONES | BAYER IP GMBH (DE) | 2015-09-02 | — | — | EP | disclosed |
| US-20140057790-A1 | 2-ACYLOXY-PYRROLIN-4-ONES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140057790-A1 | 2-ACYLOXY-PYRROLIN-4-ONES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-02-27 | — | — | US | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| WO-2007068428-A2 | INSECTICIDAL COMPOSITIONS CONTAINING PHENYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | PTEN, PIK3CG, PIK3CD | ACACB 632/4885ACACA 382/4885CYP1A2 1386/4885 |
| US-20140057790-A1 | 2-ACYLOXY-PYRROLIN-4-ONES | ATL3, PLCG2, PLCG1 | ACACB 23/4885ACACA 59/4885CYP1A2 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.