SCHEMBL11991068

SCHEMBL11991068

O=P(c1ccccc1)(c1ccccc1)c1cccc(-c2cccc(-c3cccc(P(=O)(c4ccccc4)c4ccccc4)c3)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.47
KMO O15229 1/20 0.47
PTPN1 P18031 2/20 0.44
PTPN5 P54829 1/20 0.44
GGPS1 O95749 3/20 0.43
MAOA P21397 1/20 0.43
LMNA P02545 1/20 0.42
NOTUM Q6P988 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
CA2 P00918 2/20 0.42
FDPS P14324 1/20 0.42
MMP8 P22894 1/20 0.42
MMP14 P50281 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ACMSD Q8TDX5 1/20 0.41
SMO Q99835 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13205032 1.00 HDAC8 (0.47) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL11991101 1.00 HDAC8 (0.47) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL19445013 0.98 HDAC8 (0.46) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL22174891 0.98 HDAC8 (0.46) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL11991178 0.98 HDAC8 (0.46) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL11991059 0.98 HDAC8 (0.48) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL22634016 0.98 HDAC8 (0.48) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL22174847 0.95 HDAC8 (0.47) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL10039221 0.95 HDAC8 (0.50) HDAC8KMOPTPN1PTPN5GGPS1
SCHEMBL19444838 0.93 HDAC8 (0.46) HDAC8KMOPTPN1PTPN5GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195653-B2 Scintillator and radiation detector KABUSHIKI KAISHA TOSHIBA (JP) 2025-01-14 US claimed
US-20220259491-A1 SCINTILLATOR AND RADIATION DETECTOR KABUSHIKI KAISHA TOSHIBA (JP) 2022-08-18 US claimed
US-20250031512-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-01-23 US disclosed
US-12195653-B2 Scintillator and radiation detector KABUSHIKI KAISHA TOSHIBA (JP) 2025-01-14 US disclosed
CN-118985183-A Photoelectric conversion element and imaging device 松下知识产权经营株式会社 2024-11-19 CN disclosed
US-20240008358-A1 TRIPLET QUENCHING THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-04 US disclosed
WO-2023203995-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE パナソニックIPマネジメント株式会社 2023-10-26 WO disclosed
US-20220259491-A1 SCINTILLATOR AND RADIATION DETECTOR KABUSHIKI KAISHA TOSHIBA (JP) 2022-08-18 US disclosed
US-20220112996-A1 JEWELRY AND GEM STONE LIGHTING SYSTEMS AND APPARATUSES AND METHOD MAKING AND USING SAME ASHLEY PAUL (US) 2022-04-14 US disclosed
US-20120211082-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed
US-20120211082-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLAR CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240008358-A1 TRIPLET QUENCHING CCNT1, CCNA1, CCNA2 HDAC8 4667/4885KMO 443/4885PTPN1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.