Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002055 | 0.92 | PTGER4 (0.65) | PTGER4CYP1A2CYP2D6PPARGPPARD | |
| SCHEMBL1589839 | 0.90 | PTGER4 (0.72) | PTGER4CYP1A2CYP2D6PPARDPPARA | |
| SCHEMBL14431120 | 0.88 | PTGER4 (0.62) | PTGER4CYP1A2CYP2D6PPARGPPARD | |
| SCHEMBL14430691 | 0.88 | PTGER4 (0.61) | PTGER4CYP1A2CYP2D6PPARDPPARA | |
| SCHEMBL4031837 | 0.87 | PTGER4 (0.65) | PTGER4CYP1A2CYP2D6PPARGPPARD | |
| SCHEMBL11967592 | 0.87 | PTGER4 (0.70) | PTGER4CYP1A2CYP2D6PPARGPPARD | |
| SCHEMBL1590246 | 0.87 | PTGER4 (0.83) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL13942016 | 0.87 | PTGER4 (0.83) | PTGER4CYP1A2CYP2D6PPARG | |
| SCHEMBL1589859 | 0.87 | PTGER4 (0.68) | PTGER4CYP1A2CYP2D6PPARDPPARA | |
| SCHEMBL1589990 | 0.87 | PTGER4 (0.83) | PTGER4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |