Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.70 |
| ▸ | HSD17B1 | P14061 | 7/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31209779 | 0.96 | ESR1 (0.75) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL10774275 | 0.96 | ESR1 (0.75) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL12004206 | 0.93 | ESR1 (0.61) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL12004194 | 0.91 | ESR1 (0.59) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL12005784 | 0.91 | ESR1 (0.68) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL12004569 | 0.91 | ESR1 (0.68) | ESR1ESR2HSD17B1HSD17B2AR | |
| SCHEMBL29471727 | 0.88 | ESR1 (0.80) | ESR1ESR2ARCYP3A4CYP2D6 | |
| SCHEMBL29465776 | 0.88 | ESR1 (0.80) | ESR1ESR2ARCYP3A4CYP2D6 | |
| SCHEMBL217305 | 0.88 | ESR1 (0.80) | ESR1ESR2ARCYP3A4CYP2D6 | |
| SCHEMBL12004567 | 0.85 | ESR1 (0.57) | ESR1ESR2HSD17B1HSD17B2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816135-B2 | Trisphenol compound | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220805-A1 | NOVEL TRISPHENOL COMPUND | NCOR1, NCOR2, NCOA1 | ESR1 40/4885ESR2 18/4885HSD17B1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.