⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73118 | 0.72 | — | — | |
| SCHEMBL1450328 | 0.71 | KDM4E (0.36) | — | |
| SCHEMBL27612276 | 0.70 | — | — | |
| SCHEMBL2888279 | 0.67 | — | — | |
| SCHEMBL27042 | 0.67 | — | — | |
| SCHEMBL739945 | 0.67 | — | — | |
| SCHEMBL358262 | 0.67 | — | — | |
| SCHEMBL1063869 | 0.67 | — | — | |
| SCHEMBL2186562 | 0.67 | — | — | |
| SCHEMBL2165882 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2384 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024518-B1 | Pyrazolo[4,3-C][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-07-02 | — | — | US | claimed |
| US-12018026-B1 | Pyrido[4,3-e][1,2,3]triazolo[1,5-a]pyrimidine as CK2 inhibitors | King Faisal University (SA) | 2024-06-25 | — | — | US | claimed |
| US-12018028-B1 | 5-substituted aminopyrazino[2′,1′:2,3]imidazo[4,5-c][2,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-06-25 | — | — | US | claimed |
| US-12012406-B1 | Pyrido[4,3-e]pyrrolo[1,2-a]pyrimidine as CK2 inhibitors | King Faisal University (SA) | 2024-06-18 | — | — | US | claimed |
| US-12012414-B1 | Imidazo[1,5-a]pyrido[4,3-e]pyrimidines as CK2 inhibitors | King Faisal University (SA) | 2024-06-18 | — | — | US | claimed |
| US-12012407-B1 | Pyrazolo[1,5-a]pyrido[4,3-e]pyrimidine-3-carboxylic acids as CK2 inhibitors | King Faisal University (SA) | 2024-06-18 | — | — | US | claimed |
| CN-115135656-B | Furanoindazole derivatives | 拜耳公司 | 2024-06-14 | — | — | CN | claimed |
| US-12006317-B1 | 5-substituted aminopyrimido [6′,1′:2,3] imidazo [4,5-c] [2,6] naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-06-11 | — | — | US | claimed |
| US-11999736-B1 | Pyrazino[2′,1′:2,3]imidazo[4,5-b][1,7]naphthyridines compounds as CK2 inhibitors | King Faisal University (SA) | 2024-06-04 | — | — | US | claimed |
| US-11999735-B1 | 5-substituted aminopyrimido [6′,1′:2,3] imidazo [4,5-c] [2,6] naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-06-04 | — | — | US | claimed |
| CN-87108111-A | Novel imidazole derivative and preparation method thereof | — | 1988-09-28 | — | — | CN | claimed |
| EP-0270091-A1 | Imidazole derivatives, processes for the preparation of the same, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments of therapeutic value, and intermediates formed during said processes | TANABE SEIYAKU CO., LTD. (JP) | 1988-06-08 | — | — | EP | claimed |
| EP-0244115-A2 | Phenyl-piperazine anti-arrhythmia agents | Pfizer Limited (GB) | 1987-11-04 | — | — | EP | claimed |
| CN-87102873-A | Phenylpiperazine anti-dysrhythmia agents and preparation method thereof | — | 1987-10-28 | — | — | CN | claimed |
| EP-0233051-A2 | Antiarrhythmic Agents | Pfizer Limited (GB) | 1987-08-19 | — | — | EP | claimed |
| US-4497814-A | 2-(Pyridinyl)-1,2,4-triazolo[1,5-a]pyrimidines and derivatives useful in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-02-05 | — | — | US | claimed |
| US-4127583-A | Preparation of 3-(pyridinyl)-2-cyclohexene-1-ones | STERLING DRUG INC. (US) | 1978-11-28 | — | — | US | claimed |
| US-4111946-A | Preparation of 3-(pyridinyl)-2-cyclohexen-1-ones | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | claimed |
| US-4075217-A | Conversion of 3-(pyridinyl)-2-cyclohexen-1-one to 3-(pyridinyl)anilines | STERLING DRUG INC. (US) | 1978-02-21 | — | — | US | claimed |
| US-3957758-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | claimed |