Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375832 | 0.85 | HRH3 (0.73) | HRH3KCNH2HTR3A | |
| SCHEMBL10267278 | 0.79 | HRH3 (0.69) | HRH3KCNH2HTR3A | |
| SCHEMBL13119068 | 0.78 | HRH3 (0.70) | HRH3KCNH2HTR3A | |
| SCHEMBL1372800 | 0.77 | HRH3 (1.00) | HRH3KCNH2HTR3A | |
| SCHEMBL1372883 | 0.72 | HRH3 (0.70) | HRH3KCNH2HTR3A | |
| SCHEMBL21004113 | 0.69 | HRH3 (0.84) | HRH3 | |
| SCHEMBL28285426 | 0.68 | HRH3 (0.88) | HRH3 | |
| SCHEMBL10258996 | 0.68 | HRH3 (1.00) | HRH3KCNH2HTR3A | |
| SCHEMBL1374345 | 0.68 | HRH3 (1.00) | HRH3KCNH2HTR3A | |
| SCHEMBL1374343 | 0.68 | HRH3 (1.00) | HRH3KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492263-A1 | Pyridizinone Derivatives | Cephalon, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |