Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 19/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018332 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL12004805 | 1.00 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL4901022 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3679683 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3672980 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3687025 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3679307 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL4893814 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3680464 | 0.88 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL12004356 | 0.80 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120220665-A1 | Inhibiting Neurotransmitter Reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2012-08-30 | — | — | US | disclosed |