⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484518 | 1.00 | — | — | |
| SCHEMBL15604285 | 1.00 | — | — | |
| SCHEMBL15604284 | 0.78 | GABRR1 (0.61) | — | |
| SCHEMBL18236077 | 0.78 | GABRR1 (0.61) | — | |
| SCHEMBL17465211 | 0.78 | GABRR1 (0.61) | — | |
| SCHEMBL21482195 | 0.76 | GABRR1 (0.36) | — | |
| SCHEMBL456709 | 0.75 | — | — | |
| SCHEMBL21114361 | 0.75 | GABRR1 (0.65) | — | |
| SCHEMBL2191 | 0.75 | — | — | |
| SCHEMBL565484 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911412-B2 | Derivatized chitosan polymers and methods of treating vascular disorders | SYNEDGEN, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230181623-A1 | COMPOSITIONS AND METHODS OF USE FOR WOUND HEALING | SYNEDGEN, INC. | 2023-06-15 | — | — | US | disclosed |
| US-10022393-B2 | Methods for treatment or prevention of damage resulting from radiation, trauma or shock | SYNEDGEN, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20160022564-A1 | ORAL FORMULATION OF POLYGLUCOSAMINE DERIVATIVES IN COMBINATION WITH A NON-FERMENTABLE SUGAR | SYNEDGEN INC (US) | 2016-01-28 | — | — | US | disclosed |
| US-20150038493-A1 | COMPOUNDS THAT TRAP ALPHA-OXOALDEHYDES AND ALPHA-BETA-UNSATURATED ALDEHYDES, META-COMPOUNDS CONTAINING SUCH COMPOUNDS, AND USE OF SAID COMPOUNDS IN TREATING ILLNESSES RELATED TO THE ACCUMULATION OF AGES AND ALES | PHARMAMENS (FR) | 2015-02-05 | — | — | US | disclosed |
| US-20140080785-A1 | METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK | SYNEDGEN, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8313936-B2 | Nucleic acids and polypeptides involved in the production of cryptophycin | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-20 | — | — | US | disclosed |
| US-20120220008-A1 | NUCLEIC ACIDS AND POLYPEPTIDES INVOLVED IN THE PRODUCTION OF CRYPTOPHYCIN | REGENTS OF THE UNIVERSITY OF MICHIGAN | 2012-08-30 | — | — | US | disclosed |