Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802757 | 0.83 | FFAR1 (0.66) | FFAR1FFAR4 | |
| SCHEMBL4802750 | 0.83 | FFAR1 (0.66) | FFAR1FFAR4 | |
| SCHEMBL13140282 | 0.81 | FFAR1 (0.72) | FFAR1FFAR4ACACB | |
| SCHEMBL13118297 | 0.81 | FFAR1 (0.71) | FFAR1FFAR4 | |
| SCHEMBL13118298 | 0.79 | FFAR1 (0.69) | FFAR1FFAR4 | |
| SCHEMBL13118306 | 0.79 | FFAR1 (0.69) | FFAR1FFAR4 | |
| SCHEMBL13118300 | 0.79 | FFAR1 (0.66) | FFAR1FFAR4 | |
| SCHEMBL14286119 | 0.78 | RXRB (0.56) | FFAR1 | |
| SCHEMBL1508532 | 0.78 | FFAR1 (1.00) | FFAR1 | |
| SCHEMBL13118268 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893582-B1 | Compounds, their pharmaceutical compositions and their use in treating metabolic disorders | AMGEN INC (US) | 2011-12-14 | — | — | EP | disclosed |