Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 8/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109051 | 0.84 | MEN1 (0.45) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL13109037 | 0.84 | MEN1 (0.45) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL7518298 | 0.82 | TDP1 (0.50) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL17860156 | 0.82 | TDP1 (0.50) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL25324125 | 0.82 | MEN1 (0.43) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL17788024 | 0.82 | MEN1 (0.43) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL25921359 | 0.82 | MEN1 (0.43) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL21361575 | 0.81 | TDP1 (0.46) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL14653705 | 0.81 | TDP1 (0.46) | KMT2AMEN1GAATDP1SYK | |
| SCHEMBL19371058 | 0.80 | TDP1 (0.54) | KMT2AMEN1GAATDP1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966139-B1 | ASPARTIC PROTEASE INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-12-21 | — | — | EP | disclosed |