Selfotel

Selfotel

SCHEMBL120236

O=C(O)[C@H]1C[C@@H](CP(=O)(O)O)CCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP1A2 P05177 1/20 1.00
THRB P10828 1/20 1.00
ALOX15 P16050 1/20 1.00
CYP2C19 P33261 1/20 1.00
GRIN2D O15399 1/20 1.00
GRIN3B O60391 1/20 1.00
GRIA1 P42261 1/20 1.00
GRIA2 P42262 1/20 1.00
GRIA3 P42263 1/20 1.00
GRIA4 P48058 1/20 1.00
GRIN1 Q05586 1/20 1.00
GRIN2A Q12879 1/20 1.00
GRIN2B Q13224 1/20 1.00
GRIN2C Q14957 1/20 1.00
GRIN3A Q8TCU5 1/20 1.00
KDM4E B2RXH2 1/20 0.61
ARG1 P05089 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Selfotel SCHEMBL13431267 1.00 MEN1 (1.00) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL120234 1.00 MEN1 (1.00) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL120235 1.00 MEN1 (1.00) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL20553546 1.00 MEN1 (1.00) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL16392882 1.00 MEN1 (1.00) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL9603151 0.98 MEN1 (0.97) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL9602901 0.98 MEN1 (0.97) MEN1KMT2AALDH1A1CYP1A2THRB
Selfotel SCHEMBL9603159 0.98 MEN1 (0.97) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL13431281 0.87 MEN1 (0.77) MEN1KMT2AALDH1A1CYP1A2THRB
SCHEMBL5058512 0.85 MEN1 (0.73) MEN1KMT2AALDH1A1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441087-B1 METHODS OF TREATING CHRONIC PAIN TEVA PHARMACEUTICALS INT GMBH (CH) 2025-02-19 EP claimed
CN-110831584-B Targeted drug rescue with novel compositions, combinations and methods thereof 埃克塞瓦有限责任公司 2023-03-10 CN claimed
US-20210060123-A1 THERAPEUTIC USE OF P75NTR NEUROTROPHIN BINDING PROTEIN LEVICEPT LTD (GB) 2021-03-04 US claimed
EP-3618819-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF Exciva GmbH (DE) 2020-03-11 EP claimed
US-20200069674-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF Exciva GmbH (DE) 2020-03-05 US claimed
CN-110831584-A Targeted drug rescue with novel compositions, combinations and methods thereof 埃克塞瓦有限责任公司 2020-02-21 CN claimed
EP-3441087-A1 METHODS OF TREATING CHRONIC PAIN Teva Pharmaceuticals International GmbH (CH) 2019-02-13 EP claimed
WO-2018204713-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF EXCIVA UG (HAFTUNGSBESCHRÄNKT) (DE) 2018-11-08 WO claimed
EP-2265287-B1 METHODS OF TREATING CHRONIC PAIN TEVA PHARMACEUTICALS INT GMBH (CH) 2018-09-05 EP claimed
US-20180161392-A1 THERAPEUTIC USE OF P75NTR NEUROTROPHIN BINDING PROTEIN LEVICEPT LTD (GB) 2018-06-14 US claimed
WO-1995031986-A1 COMBINATION PRODUCT OF DICHLOROACETIC ACID AND AN NMDA ANTAGONIST ASTRA AKTIEBOLAG (SE) 1995-11-30 WO claimed
EP-0533832-A4 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX US COMMERCE (US) 1993-04-28 EP claimed
EP-0533832-A1 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1993-03-31 EP claimed
EP-0488959-A2 New uses of competitive NMDA receptor antagonists SANDOZ LTD. (CH) 1992-06-03 EP claimed
WO-1991019493-A1 TREATMENT OF MOOD DISORDERS WITH FUNCTIONAL ANTAGONISTS OF THE GLYCINE/NMDA RECEPTOR COMPLEX THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1991-12-26 WO claimed
EP-0432994-A2 Excitatory amino acid antagonists as anti-emetic drugs Olney, John William (US) 1991-06-19 EP claimed
EP-0203891-B1 CERTAIN PHOSPHONIC ACIDS AND DERIVATIVES CIBA-GEIGY AG (CH) 1991-05-15 EP claimed
US-4916125-A ADMINISTERING E-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID SANDOZ LTD. (CH) 1990-04-10 US claimed
US-4898854-A NERVOUS SYSTEM DISORDERS CIBA-GEIGY CORPORATION (US) 1990-02-06 US claimed
EP-0203891-A2 Certain phosphonic acids and derivatives CIBA-GEIGY AG (CH) 1986-12-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200069674-A1 TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF HTR2A, HTR2C, CYP3A43 MEN1 3248/4885KMT2A 1669/4885ALDH1A1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.