Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426337 | 0.84 | MAOB (0.39) | — | |
| SCHEMBL12095606 | 0.84 | MAOB (0.39) | — | |
| SCHEMBL13379250 | 0.84 | MAOB (0.39) | — | |
| SCHEMBL2939389 | 0.84 | MAOB (0.39) | — | |
| SCHEMBL2939388 | 0.84 | MAOB (0.39) | — | |
| SCHEMBL12035819 | 0.81 | SLC18A3 (0.34) | — | |
| SCHEMBL21827291 | 0.81 | BACE1 (0.35) | BACE1BUB1 | |
| SCHEMBL12035830 | 0.81 | BACE1 (0.30) | BACE1 | |
| SCHEMBL12035833 | 0.81 | CYSLTR2 (0.34) | BACE1 | |
| SCHEMBL27040293 | 0.80 | SMYD2 (0.37) | BACE1BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110312990-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | BACE1 2450/4885BUB1 1593/4885 |
| US-20110312990-A1 | Diamine Derivatives | C9, C1S, C1R | BACE1 1672/4885BUB1 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.