SCHEMBL12038607

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)C(C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)C(C)NC(=O)[C@H](CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)[C@@H](NC(=O)C(NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(Cc1ccccc1)NC(=O)C(CCCCNNC(Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)NC(CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)NC(C=O)CO)[C@@H](C)O)NC(=O)C1(C)CCC/C=C\CCCC(C)(N[C@@H](CO)C(=O)C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)C(CCC(=O)O)NC(=O)[C@H](CO)NC(=O)C(Cc2ccccc2)NN)[C@@H](C)O)C(=O)C1)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	EED	O75530	1/20	0.52

▸	NPY2R	P49146	8/20	0.52

▸	NPY4R	P50391	8/20	0.52

▸	NPY5R	Q15761	8/20	0.52

▸	NPY1R	P25929	6/20	0.51

▸	TFPI	P10646	5/20	0.50

▸	GCGR	P47871	2/20	0.50

▸	KDM1A	O60341	1/20	0.50

▸	HSP90AB1	P08238	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25544142	0.88	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038559	0.88	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038621	0.86	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038668	0.86	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038577	0.86	NPY2R (0.60)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29361579	0.85	NPY2R (0.56)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038635	0.84	KDM1A (0.55)	TFPIGCGRKDM1A
SCHEMBL12038596	0.84	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038572	0.84	NPY2R (0.52)	NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL12038587	0.82	NPY2R (0.48)	NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20110318373-A1	IMMUNOSUPPRESSION MODULATING COMPOUNDS	AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN)	2011-12-29	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20110318373-A1	IMMUNOSUPPRESSION MODULATING COMPOUNDS	CD274, PDCD1, PDCD1LG2	EED 2888/4885NPY2R 3711/4885NPY4R 4103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.