Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1204546 | 1.00 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL531802 | 0.98 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6GRIK1GRIK2 | |
| SCHEMBL28904430 | 0.98 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6GRIK1GRIK2 | |
| SCHEMBL27637478 | 0.84 | SLC22A6 (0.35) | TDP1SMN1; SMN2SLC22A6MAPTHDAC2 | |
| Hydrochloric Acid SCHEMBL4148164 | 0.79 | GABRR1 (0.34) | GRIK1GRIK2GABRR1LMNA | |
| SCHEMBL5076843 | 0.78 | — | — | |
| SCHEMBL10928741 | 0.78 | — | — | |
| SCHEMBL5076842 | 0.78 | — | — | |
| SCHEMBL15447441 | 0.78 | — | — | |
| SCHEMBL40726 | 0.77 | TDP1 (0.37) | TDP1SMN1; SMN2SLC22A6GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391653-A2 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1990-10-10 | — | — | EP | claimed |
| EP-0285711-A1 | Thermally stable sulfonate compositions | KING INDUSTRIES, INC. (US) | 1988-10-12 | — | — | EP | claimed |
| US-8536103-B2 | Liquid extreme pressure additive | THE LUBRIZOL CORPORATION | 2013-09-17 | — | — | US | disclosed |
| US-20110028363-A1 | Liquid Extreme Pressure Additive | THE LUBRIZOL CORPORATION | 2011-02-03 | — | — | US | disclosed |
| EP-2250242-A2 | LIQUID EXTREME PRESSURE ADDITIVE | The Lubrizol Corporation (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009111235-A2 | LIQUID EXTREME PRESSURE ADDITIVE | THE LUBRIZOL CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |