Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28666970 | 0.86 | CYP2A6 (0.49) | CYP2A6MAOBAPPKDM4EGPR35 | |
| SCHEMBL24045462 | 0.85 | CYP2A6 (0.58) | CYP2A6MAOBAPPCA12CA9 | |
| SCHEMBL8038932 | 0.82 | APP (0.54) | CYP2A6MAOBAPPKDM4EGPR35 | |
| SCHEMBL8038933 | 0.82 | APP (0.54) | CYP2A6MAOBAPPKDM4EGPR35 | |
| SCHEMBL8784045 | 0.79 | CYP2A6 (0.44) | CYP2A6MAOBAPPKDM4EALDH1A1 | |
| SCHEMBL5144216 | 0.78 | CYP2A6 (0.65) | CYP2A6APP | |
| SCHEMBL11403521 | 0.77 | CYP2A6 (0.62) | CYP2A6MAOBAPPKDM4EALDH1A1 | |
| SCHEMBL10047130 | 0.77 | CYP2A6 (0.62) | CYP2A6APP | |
| SCHEMBL12227345 | 0.77 | CYP2A6 (0.62) | CYP2A6MAOBAPPKDM4EALDH1A1 | |
| SCHEMBL118925 | 0.77 | CYP2A6 (0.62) | CYP2A6APPKDM4EALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078720-B | Halogenated benzofuran-coumarin derivative and application thereof in preparation of anti-fouling agent | 扬州工业职业技术学院 | 2020-07-17 | — | — | CN | claimed |
| CN-110078720-A | Halogenated benzofuran-coumarin derivative and its preparing the application in fouling resistance agent | 扬州工业职业技术学院 | 2019-08-02 | — | — | CN | claimed |
| EP-4691558-A2 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | University Court of The University of Dundee (GB) | 2026-02-11 | — | — | EP | disclosed |
| US-20250295789-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2025-09-25 | — | — | US | disclosed |
| EP-2857018-B1 | Treatment or prophylaxis of proliferative conditions | UNIV COURT OF THE UNIV OF DUNDEE (GB) | 2025-09-03 | — | — | EP | disclosed |
| CN-116768877-A | ISR inhibitor and preparation method and application thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-3177601-B1 | TLR-INDEPENDENT SMALL MOLECULE ADJUVANTS | SCRIPPS RESEARCH INST (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20220031852-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2022-02-03 | — | — | US | disclosed |
| US-20220031852-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2022-02-03 | — | — | US | disclosed |
| WO-2021195603-A1 | ANTI-MALARIAL COMPOUNDS AND USES THEREOF | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) | 2021-09-30 | — | — | WO | disclosed |
| US-20200360521-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2020-11-19 | — | — | US | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-6025390-A | Heteroaromatic pentadienoic acid derivatives useful as inhibitors of bone resorption | SMITHKLINE BEECHAM SPA (IT) | 2000-02-15 | — | — | US | disclosed |
| EP-0912539-A1 | HETEROAROMATIC PENTADIENOIC ACID DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | Smithkline Beecham S.p.A. (IT) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001436-A1 | HETEROAROMATIC PENTADIENOIC ACID DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-01-15 | — | — | WO | disclosed |
| EP-0029320-B1 | SECONDARY ETHANOL AMINES, THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1985-07-10 | — | — | EP | disclosed |
| US-4341793-A | HYPOGLYCEMIC AGENTS AND DIETETICS | BEECHAM GROUP LIMITED (GB) | 1982-07-27 | — | — | US | disclosed |
| EP-0029320-A2 | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-27 | — | — | EP | disclosed |
| US-4006234-A | Substituted 2-benzofuranyl propenones as anti-tubercular agents | AMERICAN CYANAMID COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3931157-A | ANTITUBERCULAR | AMERICAN CYANAMID COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200360521-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | CYP2A6 62/4885MAOB 210/4885APP 3238/4885 |
| US-20220031852-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | CYP2A6 62/4885MAOB 210/4885APP 3238/4885 |
| US-20250295789-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, BRCA1, UGT1A1 | CYP2A6 81/4885MAOB 236/4885APP 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.