⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149261 | 0.83 | CA12 (0.35) | — | |
| SCHEMBL146748 | 0.81 | CA12 (0.40) | — | |
| SCHEMBL8773710 | 0.81 | CA12 (0.40) | — | |
| SCHEMBL643175 | 0.79 | — | — | |
| SCHEMBL7355185 | 0.75 | — | — | |
| SCHEMBL16152 | 0.74 | — | — | |
| SCHEMBL1363064 | 0.74 | — | — | |
| SCHEMBL4259471 | 0.72 | CA12 (0.44) | — | |
| SCHEMBL639312 | 0.72 | — | — | |
| SCHEMBL738626 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2826 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158397-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES THROUGH INHIBITON OF HSP90 | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2024-05-16 | — | — | US | claimed |
| CN-111892579-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-111875585-B | Kinase inhibitors | 上海艾力斯医药科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-20230125046-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-04-20 | — | — | US | claimed |
| US-11607465-B2 | Uses of labeled HSP90 inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2023-03-21 | — | — | US | claimed |
| US-20230060990-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES THROUGH INHIBITON OF HSP90 | SLOAN KETTERING INST CANCER RES (US) | 2023-03-02 | — | — | US | claimed |
| CN-113087671-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-108136330-B | Bionic membrane | 南洋理工大学 | 2022-01-11 | — | — | CN | claimed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | claimed |
| CN-113087671-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-07-09 | — | — | CN | claimed |
| US-6111045-A | YIELDS A VULCANIZED RUBBER SHOWING IMPROVEMENTS IN HEAT BUILD-UP, TENSILE STRENGTH, ABRASION RESISTANCE AND PROCESSABILITY | NIPPON ZEON CO. LTD. (JP) | 2000-08-29 | — | — | US | claimed |
| US-6030738-A | HAVING CHARGE CONTROL PROPERTIES AND HIGH THERMAL STABILITY; COMPOUNDS ARE PREFERENTIALLY WITHOUT INHERENT COLOR AND HAVE GOOD DISPERSIBILITY IN CUSTOMARY TONER, POWDER COATING AND ELECTRET BINDERS | CLARIANT GMBH (DE) | 2000-02-29 | — | — | US | claimed |
| CN-1209571-A | Use of compounding material between polyelectrolytes as charge controlling agent | CLARIANT GMBH (DE) | 1999-03-03 | — | — | CN | claimed |
| EP-0895131-A2 | Use of inner-polyelectrolyte complexes as charge controlling agent | Clariant GmbH (DE) | 1999-02-03 | — | — | EP | claimed |
| US-5700816-A | ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. | 1997-12-23 | — | — | US | claimed |
| CN-1134657-A | Herbicidal AZA bisphosphonic acid compositions | ZENECA LTD (GB) | 1996-10-30 | — | — | CN | claimed |
| EP-0063747-B1 | 2-SUBSTITUTED OR UNSUBSTITUTED AMINOCARBONYLOXYALKYL-1,4-DIHYDROPYRIDINES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-12-09 | — | — | EP | claimed |
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | claimed |
| EP-0063747-A1 | 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-11-03 | — | — | EP | claimed |
| EP-0063359-A1 | 1,4-Dihydropyridine derivatives and processes for preparing the same | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-10-27 | — | — | EP | claimed |