⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261587 | 0.63 | — | — | |
| SCHEMBL27754948 | 0.61 | — | — | |
| SCHEMBL67846 | 0.61 | — | — | |
| SCHEMBL27587062 | 0.58 | — | — | |
| Hydrogen Sulfide SCHEMBL27649694 | 0.58 | — | — | |
| Ammonia Solution, Strong SCHEMBL28253347 | 0.58 | — | — | |
| SCHEMBL11072942 | 0.58 | — | — | |
| Methane SCHEMBL27336272 | 0.58 | — | — | |
| SCHEMBL21886204 | 0.58 | — | — | |
| SCHEMBL1232382 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888355-B2 | Compositions and methods for inhibiting growth and metastasis of melanoma | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2011-02-15 | — | — | US | claimed |
| US-20100305129-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-02 | — | — | US | claimed |
| WO-2009026163-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-26 | — | — | WO | claimed |
| US-20090054438-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-26 | — | — | US | claimed |
| US-20110166216-A1 | Compositions and Methods for Inhibiting Growth and Metastasis of Melanoma | BURNHAM INSTITUTE FOR MEDICAL RESEARCH | 2011-07-07 | — | — | US | disclosed |
| US-7888355-B2 | Compositions and methods for inhibiting growth and metastasis of melanoma | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2011-02-15 | — | — | US | disclosed |
| US-20100305129-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-02 | — | — | US | disclosed |
| US-7776894-B2 | Compositions and methods for inhibiting growth and metastasis of melanoma | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| WO-2009026163-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-26 | — | — | WO | disclosed |
| US-20090054438-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-26 | — | — | US | disclosed |