Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31231224 | 1.00 | CYP1A2 (0.50) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL10953917 | 0.83 | KMT2A (0.58) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL27206810 | 0.82 | CYP1A2 (0.57) | CYP1A2PTPN1KMT2APOLBTDP1 | |
| SCHEMBL31475700 | 0.82 | CYP1A2 (0.57) | CYP1A2PTPN1KMT2APOLBTDP1 | |
| SCHEMBL4097322 | 0.82 | CNR2 (0.44) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL4096984 | 0.82 | PTPN1 (0.44) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL29254661 | 0.81 | CYP1A2 (0.48) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL344157 | 0.81 | PTPN1 (0.66) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL31522164 | 0.81 | PTPN1 (0.66) | CYP1A2PTPN1KMT2AMEN1POLB | |
| SCHEMBL9857199 | 0.81 | CYP1A2 (0.55) | CYP1A2PTPN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307394-A | Purification method of crude product of 2-methyl-6-propionylnaphthalene | 品恩赢创(苏州)新材料科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-20140031334-A1 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| CN-102026988-B | 3-substituted propanamines | SK HOLDINGS CO LTD | 2013-07-03 | — | — | CN | disclosed |
| US-8071600-B2 | Derivatives of 4-piperazin-1-yl-4-benzo[B]thiophene suitable for the treatment of CNS disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-12-06 | — | — | US | disclosed |
| CN-102026988-A | 3-substituted propanamines | SK HOLDINGS CO LTD | 2011-04-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031334-A1 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | GRIN2C, GRIN2B, PMP22 | CYP1A2 103/4885PTPN1 1331/4885KMT2A 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.