Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459768 | 1.00 | MAP3K14 (0.40) | MAP3K14NTRK1NR1H2NR1H3SYK | |
| SCHEMBL12064789 | 0.91 | NTRK1 (0.40) | MAP3K14NTRK1NR1H2KDM4DDPP4 | |
| SCHEMBL462558 | 0.90 | PDE4B (0.38) | MAP3K14NTRK1NR1H2NR1H3SYK | |
| SCHEMBL462557 | 0.90 | PDE4B (0.38) | MAP3K14NTRK1NR1H2NR1H3SYK | |
| SCHEMBL459231 | 0.86 | JAK3 (0.39) | NTRK1NR1H2NR1H3KDM4DDPP4 | |
| SCHEMBL470735 | 0.86 | NTRK1 (0.42) | NTRK1NR1H2KDM4DDPP4F2R | |
| SCHEMBL457722 | 0.85 | NTRK1 (0.41) | NTRK1NR1H2DPP4F2RNPY5R | |
| SCHEMBL457724 | 0.85 | NTRK1 (0.41) | NTRK1NR1H2DPP4F2RNPY5R | |
| SCHEMBL470545 | 0.84 | NTRK1 (0.39) | NTRK1NR1H2DPP4F2RNPY5R | |
| SCHEMBL610961 | 0.84 | NTRK1 (0.41) | NTRK1NR1H2DPP4F2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |