Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510012 | 0.91 | MAPT (0.64) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL12065084 | 0.90 | TDP1 (0.67) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL4080431 | 0.82 | MAPT (0.69) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7716471 | 0.82 | KMT2A (0.79) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL28182817 | 0.81 | TDP1 (1.00) | MAPTALDH1A1TDP1 | |
| SCHEMBL18789784 | 0.81 | MAPT (0.55) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL27358198 | 0.81 | TDP1 (0.70) | MAPTALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL8610176 | 0.81 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1AGTR1 | |
| SCHEMBL7611620 | 0.81 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL28325790 | 0.81 | KMT2A (0.70) | MAPTALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147311-A1 | HYDROXY PROPANEDIOL DERIVATIVES, THEIR PREPARATIVE METHOD, PHARMACEUTICAL COMPOSITIONS AND USE | 中国医学科学院药物研究所 (CN) | 2011-12-01 | — | — | WO | disclosed |