Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470605 | 0.84 | HRH3 (0.60) | HRH3USP30GPR119MAPTALDH1A1 | |
| SCHEMBL2300710 | 0.81 | HRH3 (0.54) | HRH3USP30GPR119MAPTALDH1A1 | |
| SCHEMBL12426822 | 0.79 | HRH3 (0.52) | HRH3USP30GPR119MAPTALDH1A1 | |
| SCHEMBL2478632 | 0.78 | HRH3 (0.57) | HRH3USP30GPR119MAPTALDH1A1 | |
| SCHEMBL2301623 | 0.77 | HRH3 (0.51) | HRH3USP30GPR119MAPTALDH1A1 | |
| SCHEMBL22396214 | 0.77 | USP30 (0.66) | HRH3USP30GPR119ALDH1A1MEN1 | |
| SCHEMBL23529148 | 0.77 | USP30 (0.55) | HRH3USP30GPR119MEN1KMT2A | |
| SCHEMBL4814583 | 0.77 | USP30 (0.55) | HRH3USP30GPR119 | |
| SCHEMBL17760752 | 0.76 | USP30 (0.56) | HRH3USP30GPR119ALDH1A1 | |
| SCHEMBL2477027 | 0.76 | HRH3 (0.51) | HRH3USP30GPR119LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148962-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF | 大正製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |