Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 18/20 | 0.53 |
| ▸ | BRAF | P15056 | 10/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986489 | 0.93 | TNNI3K (0.52) | TNNI3KBRAFWDR5KMT2A | |
| SCHEMBL9985623 | 0.91 | TNNI3K (0.48) | TNNI3KBRAFWDR5KMT2A | |
| SCHEMBL12065843 | 0.89 | TNNI3K (0.48) | TNNI3KBRAFWDR5KMT2A | |
| SCHEMBL12065858 | 0.86 | TNNI3K (0.62) | TNNI3KBRAF | |
| SCHEMBL12066380 | 0.84 | TNNI3K (0.61) | TNNI3KBRAF | |
| SCHEMBL9985744 | 0.81 | TNNI3K (0.39) | TNNI3KBRAF | |
| SCHEMBL12067895 | 0.81 | TNNI3K (0.55) | TNNI3KBRAF | |
| SCHEMBL12066375 | 0.80 | TNNI3K (0.59) | TNNI3KBRAF | |
| SCHEMBL9986084 | 0.80 | TNNI3K (0.67) | TNNI3KBRAF | |
| SCHEMBL12065551 | 0.79 | TNNI3K (0.44) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |