Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 19/20 | 0.74 |
| ▸ | BRAF | P15056 | 14/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067186 | 0.87 | TNNI3K (0.74) | TNNI3KBRAF | |
| SCHEMBL12065593 | 0.86 | TNNI3K (0.73) | TNNI3KBRAF | |
| SCHEMBL12065584 | 0.86 | TNNI3K (0.73) | TNNI3KBRAF | |
| SCHEMBL12065598 | 0.85 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067179 | 0.80 | TNNI3K (0.71) | TNNI3KBRAF | |
| SCHEMBL9980428 | 0.80 | TNNI3K (0.69) | TNNI3KBRAF | |
| SCHEMBL12065571 | 0.80 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067111 | 0.80 | TNNI3K (1.00) | TNNI3KBRAF | |
| SCHEMBL12067916 | 0.80 | TNNI3K (0.62) | TNNI3KBRAF | |
| SCHEMBL12065841 | 0.80 | TNNI3K (1.00) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |