Azepindole

Azepindole

SCHEMBL120676

c1ccc2c(c1)cc1n2CCCNC1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 11/20 0.81
HTR2C P28335 11/20 0.81
SIGMAR1 Q99720 7/20 0.40
NOTUM Q6P988 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356686 0.90 HTR2A (1.00) HTR2AHTR2CSIGMAR1NOTUM
Hydrochloric Acid SCHEMBL7842672 0.88 HTR2A (0.97) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL18911623 0.79 HTR2A (0.69) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL761931 0.77 HTR2A (0.64) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL30703022 0.77 HTR2A (0.64) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL29548539 0.75 HTR2A (0.62) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL669577 0.75 HTR2A (0.62) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL6711152 0.75 HTR2A (1.00) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL29391845 0.75 HTR2A (1.00) HTR2AHTR2CSIGMAR1NOTUM
SCHEMBL18911620 0.74 HTR2A (0.60) HTR2AHTR2CSIGMAR1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
US-20240307393-A1 PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT, COMPRISING CDK4/6 INHIBITOR AND TRICYCLIC ANTIDEPRESSANT NATIONAL CANCER CENTER (KR) 2024-09-19 US claimed
EP-4368183-A1 PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT, COMPRISING CDK4/6 INHIBITOR AND TRICYCLIC ANTIDEPRESSANT National Cancer Center (KR) 2024-05-15 EP claimed
CN-117597126-A Pharmaceutical composition for preventing or treating cancer comprising CDK4/6 inhibitor and tricyclic antidepressant 国立癌症中心 2024-02-23 CN claimed
WO-2023282544-A1 PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT, COMPRISING CDK4/6 INHIBITOR AND TRICYCLIC ANTIDEPRESSANT 국립암센터 2023-01-12 WO claimed
CN-106674280-B A kind of preparation method of phosphine oxygroup benzazolyl compounds and its derivative 广西大学 2018-05-29 CN claimed
CN-106674280-A Preparation method of phosphooxyl indole compound and derivative thereof 广西大学 2017-05-17 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
WO-2013126205-A1 MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER WARSAW ORTHOPEDIC, INC. (US) 2013-08-29 WO claimed
US-20130217673-A1 MIXED MONOAMINE REUPTAKE INHIBITOR IN A BIODEGRADABLE POLYMER CARRIER WARSAW ORTHOPEDIC, INC (US) 2013-08-22 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
US-4210590-A WITH BORANE COMPLEX REAGENT IN PRESENCE OF TRIFLUOROACETIC ACID MCNEIL LABORATORIES, INCORPORATED (US) 1980-07-01 US claimed