Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069543 | 0.89 | PDE10A (0.75) | PDE10A | |
| SCHEMBL12067672 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12067668 | 0.87 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417228 | 0.86 | PDE10A (1.00) | PDE10A | |
| SCHEMBL19372177 | 0.85 | PDE10A (0.60) | PDE10A | |
| SCHEMBL19389899 | 0.84 | PDE10A (0.87) | PDE10A | |
| SCHEMBL12069714 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL12070119 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417261 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15417682 | 0.83 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580207-B1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-09-27 | — | — | EP | disclosed |
| WO-2011154327-A1 | NITROGEN CONTAINING HETEROARYL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-15 | — | — | WO | disclosed |