Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | JAK3 | P52333 | 2/20 | 0.61 |
| ▸ | FPR1 | P21462 | 2/20 | 0.54 |
| ▸ | FPR2 | P25090 | 2/20 | 0.54 |
| ▸ | KHK | P50053 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979353 | 1.00 | EPHX1 (0.62) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL12260725 | 0.91 | EPHX1 (0.68) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL6621016 | 0.90 | EPHX1 (0.71) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL24342377 | 0.87 | EPHX2 (0.65) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL11926140 | 0.85 | EPHX1 (0.53) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL3267067 | 0.84 | KHK (0.48) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL239226 | 0.83 | POLB (0.67) | EPHX2RAB9AFPR2KHKALDH1A1 | |
| SCHEMBL239225 | 0.83 | POLB (0.67) | EPHX2RAB9AFPR2KHKALDH1A1 | |
| Hydrochloric Acid SCHEMBL28451384 | 0.81 | NPC1 (0.64) | EPHX1EPHX2SMN1; SMN2RAB9AJAK3 | |
| SCHEMBL15263046 | 0.81 | EPHX1 (0.83) | EPHX1EPHX2SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258141-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |