Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986892 | 0.94 | BRAF (0.79) | BRAF | |
| SCHEMBL986524 | 0.92 | BRAF (0.80) | BRAF | |
| SCHEMBL987246 | 0.92 | BRAF (0.80) | BRAF | |
| SCHEMBL12087600 | 0.91 | BRAF (0.63) | BRAF | |
| SCHEMBL986543 | 0.90 | BRAF (0.64) | BRAF | |
| SCHEMBL984430 | 0.90 | BRAF (0.78) | BRAF | |
| SCHEMBL986954 | 0.87 | BRAF (0.79) | BRAF | |
| SCHEMBL983982 | 0.87 | BRAF (0.78) | BRAF | |
| SCHEMBL986529 | 0.87 | BRAF (0.77) | BRAF | |
| SCHEMBL987482 | 0.86 | BRAF (0.79) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265609-B1 | IMDIZO [4. 5-B] PYRIDINE DERIVATIVES USED AS RAF INHIBITORS | ARRAY BIOPHARMA INC (US) | 2012-09-05 | — | — | EP | disclosed |