Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12091072 | 1.00 | KCNH2 (0.80) | KCNH2 | |
| SCHEMBL12046803 | 0.92 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL4298075 | 0.92 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL4299512 | 0.92 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL4306155 | 0.91 | KCNH2 (0.90) | KCNH2 | |
| SCHEMBL4294619 | 0.91 | KCNH2 (0.90) | KCNH2 | |
| SCHEMBL4140265 | 0.91 | KCNH2 (0.90) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4306127 | 0.91 | KCNH2 (0.75) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4300022 | 0.91 | KCNH2 (0.75) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4296853 | 0.90 | KCNH2 (0.89) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367831-B2 | Heterocyclic compound or salt thereof and intermediate thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120226035-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226035-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | IKZF3, ZC3HAV1L, CXXC5 | KCNH2 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.