Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831643 | 0.83 | CSNK2A1 (0.59) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17632161 | 0.83 | CSNK2A1 (0.59) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL3500308 | 0.83 | CSNK2A1 (0.59) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL29621002 | 0.83 | CSNK2A1 (0.59) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL69900 | 0.83 | CSNK2A1 (0.62) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| Bromide SCHEMBL12496053 | 0.82 | CSNK2A1 (0.57) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| Bromide SCHEMBL22834317 | 0.81 | CSNK2A1 (0.61) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL5960025 | 0.81 | CSNK2A1 (0.56) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11145599 | 0.81 | CSNK2A1 (0.61) | CSNK2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL12601168 | 0.80 | MAP4K4 (0.53) | CSNK2A1ALDH1A1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255072-B2 | Pyrazole compounds and thiazole compounds as protein kinases inhibitors | National Health Rsearch Institutes (TW) | 2016-02-09 | — | — | US | disclosed |
| CN-102993117-A | Preparation method of 2-amino-5-(4-amino phenyl)-thiazole | ZHANGJIAGANG CITY DAWEI ASSISTANTS INSDUSTRY CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-102993117-A | Preparation method of 2-amino-5-(4-amino phenyl)-thiazole | ZHANGJIAGANG CITY DAWEI ASSISTANTS INSDUSTRY CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-20120225880-A1 | PYRAZOLE COMPOUNDS AND THIAZOLE COMPOUNDS AS PROTEIN KINASES INHIBITORS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225880-A1 | PYRAZOLE COMPOUNDS AND THIAZOLE COMPOUNDS AS PROTEIN KINASES INHIBITORS | FLT4, AURKB, AURKA | CSNK2A1 945/4885ALDH1A1 3340/4885NPC1 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.