Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092014 | 1.00 | CYP1A2 (0.33) | CYP1A2KDM4EMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12092011 | 1.00 | CYP1A2 (0.33) | CYP1A2KDM4EMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12092010 | 0.87 | MCHR1 (0.43) | MTNR1AMTNR1BALDH1A1MCHR1LMNA | |
| SCHEMBL12092012 | 0.87 | MCHR1 (0.43) | MTNR1AMTNR1BALDH1A1MCHR1LMNA | |
| SCHEMBL12092013 | 0.87 | MCHR1 (0.43) | MTNR1AMTNR1BALDH1A1MCHR1LMNA | |
| SCHEMBL13696905 | 0.86 | CYP1A2 (0.37) | CYP1A2KDM4EMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14942933 | 0.83 | MCHR1 (0.45) | KDM4EMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL12134876 | 0.82 | PTGDR2 (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19PTGDR2 | |
| SCHEMBL12634564 | 0.82 | MCHR1 (0.34) | KDM4EMTNR1AMTNR1BMCHR1MAPK1 | |
| SCHEMBL14092175 | 0.80 | CYP2D6 (0.39) | CYP1A2KDM4EALDH1A1SMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120226067-A1 | PROCESSES FOR INTERMEDIATES FOR MACROCYCLIC COMPOUNDS | MARSAULT ERIC (CA) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226067-A1 | PROCESSES FOR INTERMEDIATES FOR MACROCYCLIC COMPOUNDS | MLNR, CHRM2, CCKAR | CYP1A2 942/4885KDM4E 4753/4885MTNR1A 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.