Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314229 | 0.97 | KCNH2 (0.56) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4140459 | 0.88 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL10314041 | 0.87 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL12094171 | 0.86 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL10313930 | 0.85 | KCNH2 (0.48) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4136801 | 0.85 | KCNH2 (0.56) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4141431 | 0.84 | KCNH2 (0.74) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL10313933 | 0.82 | KCNH2 (0.51) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL12002122 | 0.80 | KCNH2 (0.62) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL4137237 | 0.80 | KCNH2 (0.79) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120226035-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120226035-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF AND INTERMEDIATE THEREOF | IKZF3, ZC3HAV1L, CXXC5 | KCNH2 260/4885KCNQ1 3580/4885CACNA1C 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.