Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.53 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142176 | 0.91 | CHRM2 (0.54) | CHRM2CHRM3SCD5ACKR3HPGDS | |
| SCHEMBL2141128 | 0.85 | CHRM2 (0.58) | CHRM2CHRM3HTR2CEPHX2PTGDR2 | |
| SCHEMBL2140846 | 0.81 | CHRM2 (0.55) | CHRM2CHRM3HTR2CPTGDR2 | |
| SCHEMBL2139692 | 0.77 | CHRM2 (0.58) | CHRM2CHRM3ACKR3HPGDSHTR2C | |
| SCHEMBL2143363 | 0.76 | CHRM2 (0.61) | CHRM2CHRM3SCD5EPHX2 | |
| SCHEMBL6912745 | 0.74 | ACKR3 (0.66) | SCD5ACKR3HPGDSHTR2CPTGDR2 | |
| SCHEMBL1247151 | 0.74 | CHRM2 (0.64) | CHRM2CHRM3SCD5 | |
| SCHEMBL1246052 | 0.74 | CHRM2 (0.64) | CHRM2CHRM3SCD5EPHX2 | |
| SCHEMBL17328261 | 0.73 | EPHX2 (0.58) | CHRM2CHRM3SCD5EPHX2 | |
| SCHEMBL2142441 | 0.72 | CHRM2 (0.61) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |